The verb lose has 11 senses (first 10 from tagged texts)
1. (125) lose -- (fail to keep or to maintain; cease to have, either physically or in an abstract sense; "She lost her purse when she left it unattended on her seat")
2. (17) lose -- (fail to win; "We lost the battle but we won the war")
3. (10) lose -- (suffer the loss of a person through death or removal; "She lost her husband in the war"; "The couple that wanted to adopt the child lost her when the biological parents claimed her")
4. (7) misplace, mislay, lose -- (place (something) where one cannot find it again; "I misplaced my eyeglasses")
5. (6) lose -- (miss from one's possessions; lose sight of; "I've lost my glasses again!")
6. (4) lose -- (allow to go out of sight; "The detective lost the man he was shadowing after he had to stop at a red light")
7. (3) lose, turn a loss -- (fail to make money in a business; make a loss or fail to profit; "I lost thousands of dollars on that bad investment!"; "The company turned a loss after the first year")
8. (2) lose -- (fail to get or obtain; "I lost the opportunity to spend a year abroad")
9. (2) fall back, lose, drop off, fall behind, recede -- (retreat)
10. (1) miss, lose -- (fail to perceive or to catch with the senses or the mind; "I missed that remark"; "She missed his point"; "We lost part of what he said")
11. suffer, lose -- (be set at a disadvantage; "This author really suffers in translation")