The verb depart has 6 senses (first 4 from tagged texts)
1. (11) go, go away, depart -- (move away from a place into another direction; "Go away before I start to cry"; "The train departs at noon")
2. (5) deviate, vary, diverge, depart -- (be at variance with; be out of line with)
3. (3) depart, part, start, start out, set forth, set off, set out, take off -- (leave; "The family took off for Florida")
4. (1) depart, take leave, quit -- (go away or leave)
5. leave, depart, pull up stakes -- (remove oneself from an association with or participation in; "She wants to leave"; "The teenager left home"; "She left her position with the Red Cross"; "He left the Senate after two terms"; "after 20 years with the same company, she pulled up stakes")
6. sidetrack, depart, digress, straggle -- (wander from a direct or straight course)